Our group and Dr. Kit Lam’s group (UCD) are examining a panel of newly synthesized peptides for anti-fungal activity in order to expand the limited repertoire of anti-fungal drugs currently used to treat systemic fungal infections.

Our interest in the blood-brain barrier during pathological conditions has resulted in a collaborative study with Dr. Anne Knowlton (UCD) and Dr. Pam Lein (UCD), aimed at understanding how endothelial cell senescence during aging alters blood-brain barrier function and how that impacts the onset of dementia.

Together with Dr. George A. Thompson,  we are studying the pathogenesis of Coccidioides, the cause of Valley Fever in the southwestern United States.